"Mandy" Airs On MTV's Total Request Live

The Jonas Brothers' first single, "Mandy", was released on December 27, 2005.

Its music video was shown on MTV's Total Request Live on February 22, 2006 and reached number four. Another song, "Time for Me to Fly," was released on the Aquamarine soundtrack, also in February. In March, "Mandy" was featured in the Nickelodeon television film Zoey 101: Spring Break-Up and the Zoey 101: Music Mix soundtrack album, with Nicholas Jonas listed as the artist name. The group's music was also featured on Cartoon Network's Cartoon Cartoon Fridays. The band covered "Yo Ho (A Pirate's Life for Me)" from Pirates of the Caribbean for the DisneyMania 4 album, released on April 4, 2006.
Over the summer of 2006, the Jonas Brothers went on tour with Aly & AJ. The Jonas Brothers also created the theme song for the second season of American Dragon Jake Long, airing from June 2006 to September 2007 on the Disney Channel.

Hilary Duff has proved to be the most successful Disney star on TRL, having 3 of her videos peak at #1 on the countdown those being "Wake Up", "Beat of My Heart", and "With Love". These are not her only songs on the countdown: "Why Not" peaked at #6, both "So Yesterday" and "Come Clean" peaked at #2, "Fly" at #5, and Stranger at #6. Vanessa Hudgens premiered "Come Back to Me" which peaked at number 3, and "Say OK" which only made it to #10. The Jonas Brothers have had their songs "Hold On", and "SOS" premiere, "SOS" made it on the countdown peaking at #6. "When You Look Me in the Eyes" was on the charts for several weeks before peaking at #1, after Jonas-fans crushed and flooded the TRL site by requesting hundreds of times on March 19, 2008, "Burnin' Up" has also made it to the #1 spot on TRL. Aly & AJ's videos for "Rush" "Chemicals React" and "Potential Breakup Song" have all been on the TRL countdown with "Rush" peaking at #2 "Chemicals React" peaking at #4, and "Potential Breakup Song" peaking at #5. Ashley Tisdale premiered "He Said She Said", with this she has the most successful music video by a Disney star on TRL, because reached the #1 spot for sixteen days and these was retrieved at 40 days in the countdown. Miley Cyrus's "7 Things" premiered on TRL and reached #4 on the show.