FDA Approver Bayer Healthcare's Nexavar
Nexavar is a cancer (chemotherapeutic) medication.
Nexavar interferes with the growth of cancer cells and slows their growth and spread in the body.
Nexavar is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer.
This medication is used to treat kidney or liver cancer. Sorafenib stops or slows the growth of cancer cells (tumors). It also works by slowing the growth of new blood vessels within the tumor.
Nexavar (sorafenib) is a multikinase inhibitor targeting a number of serine/threonine and receptor tyrosine kinases. Inhibition of these systems inhibits division and growth of tumor cells, and potentiates cellular apoptosis.
Nexavar is specifically indicated for the treatment of advanced renal cell carcinoma (RCC).
Nexavar is supplied as a orally available tablet; each tablet contains 200 mg of the drug. Recommended dosage is 400 mg (two tablets) twice daily. As necessary, dose may be reduced to 400 mg once daily or once every other day to manage treatment-related toxicity.