FDA Approves Daiichi-Sankyo's Benicar to Lower Hypertension

Benicar controls high blood pressure.

It works by blocking the effect of a hormone called angiotensin II. Unopposed, this substance prompts the blood vessels to contract, an action that tends to raise blood pressure. Benicar relaxes and expands the blood vessels, allowing pressure to drop. Benicar may be prescribed alone or with other blood pressure medications, such as diuretics that help the body get rid of excess water.

Benicar is a member of the angiotensin II receptor blocker (ARB) class.
The U.S. Food and Drug Administration (FDA) granted marketing approval for Benicar for the treatment of hypertension in April 2002.
Benicar/Benicar HCT was ranked #3 in the ARB class for number of prescriptions (TRx).1,2
Benicar is indicated for first-line therapy for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
Benicar blocks the vasoconstrictor effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in vascular smooth muscle. Angiotensin II is a potent vasoconstrictor that increases blood pressure in the body.
Studies in mild-to-moderate patients show that Benicar 20 mg — the usual recommended starting dose — resulted in significant mean reductions vs. baseline at trough in systolic and diastolic blood pressure of up to 15/12 mm Hg (mean placebo reductions of 6/6 mm Hg).

When suffering from high blood pressure, fatigue, lethargy and body aches and pains are quite common. With high blood pressure as a leading indicator of cardiovascular ailments, seeking the appropriate medical attention


is crucial to ensuring optimal cardiovascular health outcomes. When coping with a simple case of high blood pressure, discuss the use of FDA approved Benicar in the fight to improve cardiovascular health. Understanding the dosing recommendations of Benicar, the side effects and contraindications will ensure the patient is well versed in the anticipated outcome of this high blood pressure treatment.
Benicar, manufactured and distributed by Daiichi Sankyo, Inc. and Forest Pharmaceuticals, Inc., lends its success to controlling high blood pressure through its ability to block hormones which impact the change in blood vessel constriction. With the use of Benicar, in the treatment of high blood pressure, the hormone is negated thereby allowing blood vessels to dilate resulting in a drop in blood pressure.