FDA Approves AstraZeneca's Entocort EC

Treating mild to moderate Crohn disease and maintaining remission for up to 3 months.

It may also be used for other conditions as determined by your doctor.

Entocort EC Sustained-Release Capsules are a corticosteroid. It works by decreasing inflammation.

This medication is used to treat mild to moderate symptoms of a bowel condition called Crohn's disease. While budesonide does not cure this condition, it may help relieve symptoms such as abdominal pain and soft/liquid stools and may decrease the need for anti-diarrhea medications. Budesonide is a corticosteroid that works by decreasing swelling (inflammation).

What is Entocort EC?

Entocort EC is used to treat mild to moderate Crohn's disease involving the ileum and/or the ascending colon. Entocort EC is a nonsystemic corticosteroid that is released into the intestine and works to reduce inflammation. Because 90% of the drug is released in the intestine and not into the bloodstream, it causes fewer side effects than other corticosteroids (i.e., prednisone).

How is Entocort EC taken?

Entocort EC is normally taken in capsue form in the morning with or without food. Entocort EC should be swallowed whole and should never be crushed, chewed or broken in half.

Entocort EC has been approved by the FDA for the treatment of mild-to-moderate, active Crohn's disease involving certain sections of the small and large intestines (ileum and/or ascending colon). This once-daily medication targets the intestines and is then quickly metabolized, this reduces the amount of drug entering the systemic circulation, potentially reducing side effects.

According to the Crohn's & Colitis Foundation of America, there may be up to 1,000,000 Americans with inflammatory bowel disease (IBD). The category of IBD includes both Crohn's disease and ulcerative colitis, two similar disorders of unknown origin. Crohn's disease typically occurs in the ileum and colon, but it can take place in any section of the gastrointestinal tract. Symptoms of the disorder can include diarrhea, crampy abdominal pain, fever and sometimes bleeding from the rectum.