FDA Approves Abbott's Kaletra

Kaletra, a combination of antiviral medications lopinavir and ritonavir, belongs to a group of HIV medicines called protease inhibitors.

These medicines prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

Kaletra is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Kaletra is not a cure for HIV or AIDS.

KALETRA is a prescription anti-HIV-1 medicine called a protease inhibitor that contains lopinavir and ritonavir. KALETRA is used with other anti-HIV-1 medicines to increase the chance of treatment response in people with human immunodeficiency virus (HIV-1) infection. It is not known if KALETRA is safe and effective in children under 14 days old.

KALETRA does not cure HIV-1 infection or AIDS and does not stop you from passing HIV-1 to others. You may still get opportunistic infections or other conditions that happen with HIV-1.

Kaletra is an HIV medication. It is in a category of HIV medicines called protease inhibitors (PIs). Kaletra prevents cells infected by HIV from producing new virus. This reduces the amount of virus in your body, and can increase the number of CD4 cells.

Kaletra, sold as Aluvia in some parts of the world, is manufactured by Abbott Laboratories. The U.S. Food and Drug Administration (FDA) approved it for the treatment of HIV infection, in both adults and children, in 2000.

Kaletra is actually two drugs combined into a single capsule: lopinavir and low dose ritonavir (Norvir), another protease inhibitor manufactured by Abbott Laboratories. This is because ritonavir increases the amount of lopinavir in the blood, thus making it more effective against HIV.

This combination product contains two medications, lopinavir and ritonavir. This product is used in combination with other medications to help control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV disease complications (e.g., opportunistic infections, cancer). Both lopinavir and ritonavir belong to a class of drugs known as HIV protease inhibitors. The ritonavir in this product helps the lopinavir to stay in your body. This effect builds up the amount of lopinavir in your body, increasing its effectiveness.

This lopinavir/ritonavir product is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).