FDA Approves Salix Pharms's Colazal

Treating mildly to moderately active inflammation of the colon (ulcerative colitis). It may also be used for other conditions as determined by your doctor.

Colazal is an anti-inflammatory. How it works is not fully known. It appears to reduce ulcerative colitis (inflammation of the colon) by preventing the production of substances that cause the inflammation.

Balsalazide is used to treat a certain bowel disease (ulcerative colitis). It helps to reduce symptoms of ulcerative colitis such as diarrhea, rectal bleeding, and stomach pain. Balsalazide is an anti-inflammatory drug that works by decreasing swelling in the colon.

Colazal is used in the treatment of mild to moderate ulcerative colitis (chronic inflammation and ulceration of the lower intestine). It is an anti-inflammatory medicine specially formulated to release the active ingredient, mesalamine, directly to the lining of the colon. Its ability to provide relief without the severe side effects found with similar drugs is believed to be due to this localized drug delivery mechanism.

What Is Colazal?

Colazal (balsalazide disodium) is used to treat mild to moderately active ulcerative colitis. It is approved for use in patients over the age of 5 years. Colazal is an anti-inflammatory medication that is released in the large intestine, where the drug works topically to decrease the inflammation caused by ulcerative colitis.

How Is Colazal Taken?

Colazal is normally taken by adults in doses of three capsules three times per day with or without food. The drug was approved for kids age 5 to 17 after being studied in a small group of children; the two doses studied were one capsule three times a day and three capsules three times a day. Colazal is proven safe if taken for 8 weeks (kids) or 12 weeks (adults).

If capsules can not be swallowed, they may be opened and the contents sprinkled on applesauce. The applesauce should be eaten right away. If Colazal is taken in this way, it may cause a stain on the teeth or on the tongue.