Ronald Reagan Appears as George 'The Gipper' Gipp in "Knute Rockne, All American"
Knute Rockne, All American is a 1940 biographical film which tells the story of Knute Rockne, perhaps the most famous of all of the football coaches at Notre Dame, one of the most successful football programs in history.
It stars Pat O'Brien, Ronald Reagan, Gale Page, Donald Crisp, Albert Bassermann, Owen Davis, Jr., Nick Lukats, Kane Richmond, William Marshall and William Byrne. It also included a cameo by legendary football coach Amos Alonzo Stagg, who played himself. The role of "George 'The Gipper' Gipp" by Ronald Reagan gave him the nickname of "The Gipper" for the rest of his life.
The movie was written by Robert Buckner and directed by Lloyd Bacon. In 1997, this film was deemed "culturally, historically, or aesthetically significant" by the United States Library of Congress and selected for preservation in their National Film Registry.
Trivia note: In the Lux Radio Theatre broadcast (12-2-1940) of the movie, Fay Wray portrayed Mrs. Rockne.
 "Win one for the Gipper"
“ The last thing George said to me, 'Rock,' he said, 'sometime when the team is up against it and the breaks are beating the boys, tell them to go out there with all they've got and win just one for the Gipper.' ”
This quote is ranked #89 on a poll of AFI 100 Years...100 Quotes. The phrase "Win one for the Gipper" was later used as a political slogan by Ronald Reagan, who was often referred to as "The Gipper". A famous use of it was at the 1988 Republican National Convention when Reagan told his Vice President George H. W. Bush, "George, go out there and win one for the Gipper." It was also used in the 2004 Republican National Convention by President George W. Bush in his acceptance speech when he stated "we can now truly win one for the Gipper," shortly after Reagan's death.
The speech is parodied in the movie Airplane!