Arthritis Treatment History Events

4500BC The First Case of Arthritis in Humans in Native Americans From Tennessee and Kansas
In 4500 BC, arthritis was first discovered in human beings. It was seen in the skeletal remains of Native Americans of Tennessee and parts of modern-day Olathe, Kansas, USA.
2590BC Evidence of Arthritis in Mummy, Otzi the Iceman
Evidence of arthritis has been found throughout history, from Otzi, a mummy (circa 3000 BC) found along the border of modern Italy and Austria, to the Egyptian mummies circa 2590 BC.
500BC Willow Bark First Used to Relieve Symptoms of Arthritis
Around 500 BC, a wonder drug, known as the willow bark came into prominence when it became known that it had the power to relieve gained popularity when it was discovered that this bark c...
1820 European Scientists Discover Salicin as the Active Ingredient in Willow Bark that Treats Arthritis
It wasn't until more than 2000 years later, in the early 1820s, that European scientists began to scientifically study what the chemical compound was in willow bark that alleviated the ar...
1897 Felix Hoffman, an Employee of Bayer Company, Learned How to Isolate Salicin and Make it Pleasant to the Stomach
Once they isolated salicin, they found it was poisonous to the stomach. Then, 80 years later, in 1897, Felix Hoffman, an employee of Bayer Company, (a dye production company) learnt just ...
1899 Bayer Company Trademarked Hoffman's Discovery Under the Name "Aspirin"
In 1899, Bayer Company trademarked Hoffman's discovery under the name "Aspirin." Today it is believed that over a trillion tablets of aspirin have been sold worldwide.
1953 Dec 7 FDA Approves Dava's Methotrexate
Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Methotrexate is ...
1955 Apr 18 FDA Approves Sanodi Aventis's Plaquenil
Plaquenil is considered an older disease-modifying anti-rheumatic drug or DMARD. Plaquenil is actually in a class of medications called anti-malarials but it is also used to treat rheumat...
1959 May 18 FDA Approves Pharmacia and UpJohn's Solu-Medrol Solution
Treating certain conditions associated with decreased adrenal gland function. It is also used to treat severe inflammation caused by certain conditions, including severe asthma, severe al...
1965 Jun 10 FDA Approves Iroko's Indocin
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that reduces fever, pain and inflammation. It is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve). Indomethacin w...
1968 Mar 20 FDA Approves Prometheus's Imuran
Preventing kidney transplant rejection along with other medicine. It may also be used to treat signs and symptoms of active rheumatoid arthritis. It may also be used for other conditions ...
1974 Sep 19 FDA Approves McNEIL's Motrin
Motrin is a nonsteroidal anti-inflammatory drug available in both prescription and nonprescription forms. Prescription Motrin is used in adults for relief of the symptoms of rheumatoid ar...
1976 Mar 11 FDA Approves Roche Palo's Naprosyn
Naprosyn is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. Naprosyn is used...
1984 May 18 FDA Approves Wyeth's Advil
Advil (ibuprofen) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ibuprofen works by reducing hormones that cause inflammation and pain in the body. Advil ...
1988 Jul 28 FDA Approves Novartis's Voltaren
Voltaren is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Voltaren works by reducing hormones that cause inflammation and pain in the body. Voltaren is used...
1992 Oct 29 FDA Approves GD Searle's Daypro
Treating rheumatoid arthritis, osteoarthritis, or juvenile arthritis. It may also be used for other conditions as determined by your doctor. Daypro is an NSAID. Exactly how it works is...
1994 Jan 11 FDA Approves Bayer's Aleve
Aleve (naproxen) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. Aleve is...
1995 Jul 14 FDA Approves Novartis's Neoral
Preventing the rejection of organ transplants (kidney, liver, and heart). Neoral is also used to treat psoriasis and rheumatoid arthritis in certain patients. It may also be used for othe...
1997 Dec 24 FDA Approves GD Searle's Arthortec
Arthrotec is a tablet containing a combination of diclofenac and misoprostol. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflam...
1998 Aug 24 FDA Approves Centocor's Remicade
Remicade reduces the effects of a substance in the body that can cause inflammation. Remicade is used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, Crohn's di...
1998 Nov 2 FDA Approves Immunex's Enbrel
Enbrel works by decreasing a certain protein produced by the immune system. The immune system helps the body fight infections. In people with autoimmune disorders, the immune system mista...
1998 Dec 31 FDA Approves GD Searle's Celebrex
Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis, ankylosing spondylitis (rheumatoid arthritis of the spine), and rheumatoid arthri...
2000 Apr 13 FDA Approves Boehringer Ingelheim's Mobic
Mobic is a once-daily, 7.5 mg tablet indicated for the relief of the pain and stiffness associated with osteoarthritis. Mobic is a non-steroidal anti-inflammatory drug (NSAID). Osteoarth...
2001 Mar 21 FDA Approves BARR's Trexall
Treating certain types of cancer, severe psoriasis, or rheumatoid arthritis in certain patients. It may be used alone or with other medicines. It may also be used for other conditions as ...
2002 Dec 31 FDA Approves Abbott's Humira
Humira reduces the effects of a substance (tumor necrosis factor alpha) in the body that can cause inflammation. Humira is used to treat rheumatoid arthritis, juvenile idiopathic arthr...
2008 Apr 22 FDA Approves UCB Inc's Cimzia
Cimzia is in a group of drugs called tumor necrosis factor blockers. Certolizumab reduces the effects of a substance in the body that can cause inflammation. Cimzia is used to treat th...
2010 Jun 3 University of Manchester Study Finds Meditation Helps Ease Pain of Arthritis
To reach the conclusion, scientists from The University of Manchester recruited individuals into the study who had a diverse range of experience with meditation, spanning anything from mo...