Baghdad governor Ali al-Haidri has been assassinated in the capital, police and hospital sources say.
Details of al-Haidri's death on Tuesday remain unclear.
Al-Haidri is the most senior Iraqi official to be assassinated in Baghdad since the head of the Governing Council was killed by a bomb in May last year.
He had survived a previous assassination attempt in September.
Armed fighters have repeatedly targeted Iraqi officials as well as the country's fledgling security forces as part of a fierce effort to destabilise the US-backed interim government.