Jan 2004
Caduet combines the drugs amlodipine (Norvasc, Lotrel) and atorvastatin (Lipitor), two widely prescribed cardiovascular medications. It's the first medicine to treat two different conditions, high blood pressure and high cholesterol.
It is indicated for the treatment of hypertension, chronic stable angina and vasospastic angina (Prinzmetal’s or variant angina). It is also indicated for primary dysbetalipoproteinemia, elevated serum TG levels, hypercholesterolemia and mixed dyslipidemia. In addition, is indicated as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia
The recommened initial antihypertensive oral dose of amlodipine is 5 mg once daily with a maximum dose of 10 mg once daily.