The 1943 NCAA Men's Division I Basketball Tournament involved 8 schools playing in single-elimination play to determine the national champion of men's NCAA Division I college basketball. It began on March 24, 1943, and ended with the championship game on March 30 in New York City. A total of 9 games were played, including a third place game in each region.
Wyoming, coached by Everett Shelton, won the national title with a 46-34 victory in the final game over Georgetown, coached by Elmer Ripley. Ken Sailors of Wyoming was named the tournament's Most Outstanding Player.